Innovation activities contribute essentially to the national dimension and growth. The technological infrastructure and innovation capabilities affect not only the national growth, but also the whole periphery and economy as well. There are a lot of problems and questions regarding the measurement of innovation activities at a national or regional level. This training course attempts to analyze the whole framework of innovation statistics and in particular to examine the measurement and also the statistical estimation of innovation activities. On this context, it is also designed to emphasize and to review the appropriate techniques, the most common methods and the particular problems associated with economic modeling of innovation. The program is well-suited to young innovators and entrepreneurs interested in the development of socially-beneficial products and ideas.